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Does formaldehyde react with HCN?
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Yes, formaldehyde (HCHO) reacts with hydrogen cyanide (HCN) in a nucleophilic addition reaction to form formaldehyde cyanohydrin, also known as glycolonitrile.
Reaction:
HCHO + HCN → HOCH2CN
This reaction is an example of cyanohydrin formation. The cyanide ion (CN-) acts as a nucleophile, attacking the electrophilic carbonyl carbon of formaldehyde. The proton from HCN then protonates the oxygen atom, resulting in the formation of the cyanohydrin.