A.P.J. Abdul Kalam had to part ways with his close friends due to differing life choices and career paths. His friends, Ramanadha Sastry, Aravindan, and Sivaprakasan, chose to continue their families' traditional occupations after finishing their education, while Kalam pursued higher education and a career in science and engineering outside of their hometown, Rameswaram.

• Ramanadha Sastry: Took over the priesthood of the Rameswaram temple from his father.
• Aravindan: Went into the business of arranging transport for visiting pilgrims.
• Sivaprakasan: Became a catering contractor for the Southern Railways.

Kalam's ambition and pursuit of scientific endeavors led him away from Rameswaram, causing a natural separation as they followed their own destinies.