Dr. Sadao Hoki was a Japanese surgeon and scientist featured in the story "The Enemy" by Pearl S. Buck.

In the story, Sadao and his wife, Hana, find an injured American prisoner of war and must decide whether to turn him in or treat him, despite the risks to themselves and their family during World War II. Ultimately, they choose to operate on him and help him escape.

Dr. Sadao is portrayed as a dedicated doctor torn between his duty to his country and his humanitarian instincts.